Principal Scientist, Molecular Design

Location: Remote
Compensation: To Be Discussed
Reviewed: Fri, May 09, 2025
This job expires in: 14 days
Computational Chemistry Medicinal Chemistry Ligand-based Methods Structure-based Methods

Job Summary

A company is looking for a Principal Scientist, Molecular Design.

Key Responsibilities
  • Lead multiple pipeline programs through hit exploration and hit-to-lead, setting strategies for progression into lead optimization
  • Manage multiple direct reports leading efforts on pipeline projects
  • Design small molecules using high-throughput computational tools and collaborate with various teams to develop generative design tools
Required Qualifications
  • BS/MS/Ph.D in computational, organic, or medicinal chemistry, or a related field
  • 7 or more years of experience as a computational or medicinal chemist in industry
  • Publications and patents demonstrating design contributions
  • Experience with ligand-based and structure-based methods for small molecule design
  • Familiarity with Python and RDKit
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